Five Indian-origin CEOs transforming major American industries

From YouTube to Molson Coors, innovation leads the way

Five Chief Executive Officers of Indian-origin, including those running YouTube, Wayfair, Vertex, T-Mobile, and Molson Coors, are redefining American industries with bold innovation, global strategies, and a focus on transformative business growth.

Beyond the headline-grabbing executives of Indian origin leading global heavyweights like Google or Microsoft, there are several other Indians or Persons of Indian Origin at the helm of a multitude of other companies in the United States. Here are a few of them.

Neal Mohan, CEO, YouTube

Neal Mohan has led YouTube, the world’s largest digital video platform, since February 2023. Under his leadership, YouTube generated approximately USD 40 billion in revenue during 2023, sustaining its position as one of Alphabet’s most lucrative businesses. Mohan is credited for introducing innovative features like YouTube Shorts to rival TikTok and enhancing monetisation for creators, reinforcing YouTube as a creator-centric ecosystem.

His previous successes at DoubleClick and a deep understanding of digital advertising have shaped YouTube’s growth trajectory and content recommendations. As of 2024, his estimated net worth exceeds USD 50 million.

Niraj Shah, CEO, Wayfair

Niraj Shah co-founded Wayfair in 2002 and has remained its CEO ever since, transforming the company into the largest US online retailer for home goods. Wayfair reported USD 11.9 billion in net revenue for 2024 and operates across North America and Europe with a workforce of over 12,000. Shah’s data-driven leadership style and focus on customer-centric logistics have played a pivotal role in Wayfair’s expansion. Beyond business, Shah co-founded the Shah Family Foundation, which funds education and healthcare initiatives.

Reshma Kewalramani, CEO, Vertex Pharmaceuticals

Reshma Kewalramani leads Vertex Pharmaceuticals, overseeing the first-ever Crispr-based gene therapy for sickle cell disease that has been approved by the United States Food and Drug Administration (FDA), a historic leap in biomedicine. As CEO since 2020, she has expanded Vertex’s therapy portfolio to include cutting-edge treatments for cystic fibrosis and rare genetic disorders.

With a backdrop in nephrology and internal medicine, Kewalramani prioritises both scientific innovation and regulatory excellence. Recently named among the 2025 TIME100, she has inspired transformation across the industry by championing diversity, technology-driven healthcare, and translational drug discovery.

Srini Gopalan, Incoming CEO, T-Mobile

Srini Gopalan will take charge as T-Mobile’s CEO beginning November 1, after serving as COO and previously leading Deutsche Telekom’s German business. Gopalan specialises in technology leadership and customer-first digital transformation. As CEO of the German division, he doubled growth rates and steered major fiber network expansions. At T-Mobile, an American wireless network operator based in Washington, he has already helped drive substantial acquisitions and positioned the company as a 5G leader. Gopalan, an alumnus of IIM-Ahmedabad, brings a global perspective after leadership stints at Vodafone, Bharti Airtel, and Capital One.

Rahul Goyal, CEO, Molson Coors

Rahul Goyal, with a 24-year tenure at Molson Coors, a beverage company, based in Chicago, became CEO on October 1. Starting his career in Golden, Colorado, Goyal held critical roles in IT, finance, and global strategy, notably as Chief Strategy Officer. He managed key brand expansions and spearheaded the company’s partnership strategy, helping Molson Coors adapt in the evolving beverage landscape. Goyal holds a mechanical engineering degree from the University of Mysore and dual master’s degrees from the University of Denver.